Post-bariatric hypoglycemia toll, avexitide trial design at ENDO 2026
Amylyx Pharmaceuticals will present two posters at ENDO 2026 detailing the burden of post-bariatric hypoglycemia (PBH) in the U.S. and the participant-informed design of its Phase 3 LUCIDITY trial for avexitide. Avexitide, a first-in-class GLP-1 receptor antagonist, has received Breakthrough Therapy Designation for both PBH and congenital hyperinsulinism, and aims to address the lack of FDA-approved therapies for PBH. The LUCIDITY trial is evaluating avexitide's efficacy and safety in reducing hypoglycemic events in PBH patients.
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